Testosterone is the hormone that makes men, men. Produced in the testicles, it’s the driving force behind muscle growth, body and facial hair, a deeper voice, and even sperm production. It’s what fuels male sexual development, especially during puberty. But as you age, testosterone levels drop—it’s just biology. For some men, those levels drop too low. That’s called Testosterone Deficiency Syndrome (TD) or Low Testosterone (Low T). When your body doesn’t have enough testosterone, you can feel the difference, and it’s not something you have to accept.

Low testosterone, or hypogonadism, hits hard in many areas—physically, sexually, emotionally, and mentally. Physically, it can lead to fatigue, muscle loss, weaker bones, added body fat, and urinary issues. Sexually, men may face a drop in libido, erectile dysfunction, and fewer morning erections. Emotionally and mentally, it can trigger depression, mood swings, and problems with focus and memory. Other signs include hair loss, breast tissue development (gynecomastia), and infertility. These symptoms can seriously impact your quality of life, so it’s important to get checked if you’re experiencing any of them.

KYZATREX® is an FDA-approved oral testosterone for men who have low or no testosterone levels due to certain medical conditions. KYZATREX® is a controlled substance (CIII) because it contains testosterone. It is not known if KYZATREX® is safe or effective in males younger than 18 years old. Improper use may affect bone growth in children. KYZATREX® is not meant for use by women. KYZATREX® is an immediate-release oral testosterone undecanoate. It is absorbed through the lymphatic system, where the body then uses it to replace testosterone that has been lost as a result of various medical conditions.

KYZATREX® is a controlled substance (CIII) because it contains testosterone. It is not known if KYZATREX® is safe or effective in males younger than 18 years old. Improper use may affect bone growth in children. KYZATREX® is not meant for use by women. In the phase 3 clinical trial for KYZATREX® (n=155), 4 patients (2.6%) reported high blood pressure. A total of 5 patients (3.2%) began taking new antihypertensive medications after study start. No patient increased their dose of antihypertensive medication. Your healthcare provider will monitor your blood pressure while you are being treated with KYZATREX®. If your blood pressure increases, you may need to start medication to control your blood pressure. If you are currently taking blood pressure medicines, they may need to be changed or new blood pressure medicines may need to be added. If your blood pressure cannot be controlled, KYZATREX® may need to be stopped. KYZATREX® is not bad for your liver. You may have heard about older forms of oral testosterone being liver toxic. The good news is that KYZATREX® was specifically designed to be absorbed lymphatically. This means it bypasses your liver avoiding the liver toxicity associated with oral testosterone medications of the past.

Fill out our 5-minute questionnaire to get started. Be prepared to answer questions related to your health history and goals. Once you submit your payment, we'll help schedule your hormone panel with one of our lab partners. (Labs are included in the price—all you have to do is show up).

Next, you'll schedule a video call with your Thrive physician. This isn’t a quick screening; it’s your dedicated time to discuss your goals, ask questions, address any concerns, and get clarity on what to expect before your first dose. Once approved, your prescription will be mailed directly to you.

Yes, after completing the sign up process, you'll schedule your hormone panel and then schedule a video visit with one of our board-certified doctors. They're not just going to write a prescription and send you on your way. You get thoughtful, ongoing medical care—not a preset protocol.

Your Thrive physician will take their time to understand the full picture. Every decision is grounded in clinical expertise and made with your goals in mind so you feel confident every step of the way. By signing up, you unlock trusted, personalized guidance before your treatment even begins.

Oral TRT offers a convenient and effective alternative to testosterone replacement—without the pain that comes from injections. Same results, less hassle.

Some patients could experience one or more of the following side effects from TRT:

• Increase in red blood cells. This can be beneficial if you have anemia. However, it can be potentially dangerous because an increase in red blood cells can lead to blood clots, heart attack, or stroke.
• Prostate effects. If you have an enlarged prostate, testosterone may worsen your symptoms, particularly if you are more than 50 years of age. If you have a history of prostate cancer, you cannot receive testosterone therapy without prior clearance from the urologist who is overseeing your care.
• Skin reactions. Acne, oily skin, increased body hair, and flushing have been reported. These side effects are not very common, but if they occur, often they are transient.
• Infertility. Testosterone therapy down regulates production of a man’s sperm. Be upfront with your medical provider about your desire for children and be sure to discuss the situation with your spouse or partner, if appropriate.
• Sleep apnea. This is a condition that disrupts breathing during sleep, and if already present, may be worsened by the use of testosterone therapy. If you snore or suspect you may have sleep apnea, be sure to talk to your medical provider about the situation. Considering a sleep study for further evaluation may be appropriate prior to starting therapy.
• Fluid retention. Although uncommon, you must use caution if you have a history of heart failure or kidney disease.